Drugs.com provides accurate and independent information on more than 24,000 prescription drugs, over-the-counter medicines and natural products. Caffeine in guarana passes into breast milk and can affect a nursing baby. Its secret ingredient? Find out more about this vine here. This is not a complete list of side effects and others may occur. Her work is regularly featured in media such as First For Women, Woman's World, and Natural Health. Side effects depend on the dose. Generic Name: guarana (GWAR ah na)Brand Name: Medically reviewed by Drugs.com on Jul 24, 2020 – Written by Cerner Multum. In Brazil, guarana drinks are considered "health tonics" and are almost as popular as traditional cola-based sodas. Guarana is used for weight loss, to enhance athletic performance, as a stimulant, and to reduce mental and physical fatigue. 3. Guarana contains more than 2.5% to 5% caffeine by weight. Health and technological aspects of methylxanthines and polyphenols from guarana: A review. 2005;24(6):1019-1028. doi:10.1016/j.clnu.2005.08.004, Baghkhani L and Jafari M. Cardiovascular adverse reactions associated with Guarana: is there a causal effect?. The rising popularity of guarana worldwide and the competitive pressure of commercial growers from abroad has led to the decline of guarana and traditional methods of cultivation. Guarana is a plant and it is also known as Brazilian Cocoa, Cacao Brésilien, Guarana Seed Extract, Guaranine, Paullinia cupana, Paullinia sorbilis, Zoom. 2014. The guarana plant is traditionally used to help prevent and treat malaria. Guarana plays an important role in the mythology of the Sateré-Mawé people of Brazil, for whom the word guaraná translates to "the beginning of all knowledge." doi:10.3390/nu7010196, Santana, Á. L., Macedo, G. A. Journal of Functional Foods. Although not all side effects are known, guarana is thought to be likely safe for most people when taken in amounts commonly found in foods. Tell each of your health care providers about all medicines you use now and any medicine you start or stop using. Today, guarana seeds are still used as medicine. What Is Cannabis and What Can It Be Used For? Nevertheless, it's worth digging into what is proven (and not). doi:10.1089/acm.2010.0571, Dorneles, I. M. P., Fucks, M. B., Fontela, P. C., Frizzo, M. N., & Winkelmann, E. R. Guarana (Paullinia cupana) presents a safe and effective anti-fatigue profile in patients with chronic kidney disease: A randomized, double-blind, three-arm, controlled clinical trial. It’s also been found to help promote learning. Guarana can be eaten raw and heals up to 1,950 life points each. If you use guarana, do it moderation, and don’t exceed the recommended dose. Some products used to treat cellulitis have also incorporated guarana and its various parts because of its high caffeine content. 2014;7(1):196-208. This material is provided for educational purposes only and is not intended for medical advice, diagnosis or treatment. Combining guarana with ma huang may increase the risk of stroke, hemorrhage, myocardial infarction, and sudden death, and has been associated with increases in heart rate, blood pressure, and potentially harmful changes in glucose and potassium levels. Guarani is a language indigenous to South America. Guarana Side Effects. Due to its high caffeine content, it is most known for being an energy supplement. What is guarana used for? It's important to note that these effects cannot be attributed to the guarana alone, and eight of the 35 study participants receiving the guarana-ma huang combination quit the study early as a result of unwanted side effects—insomnia and headache being among the most frequently reported. Guarana is a natural herbal supplement. Many people who consume beverages containing guarana are devotees, and they may not concern themselves with research that proves how the drinks make them feel. A guarana is added to a Skeka flask (unfinished) to create a Skeka flask (partial mix), a … 2018. Guarana is a rainforest vine growing in the Amazon region in Brazil. These are all natural stimulants. Guarana is widely used in the food industry in the form of syrups, extracts, and distillates, primarily as a flavouring agent and as a source of caffeine by soft drink manufacturers. Cardiovascular adverse reactions associated with Guarana: is there a causal effect? Guarana powder has been used for its excellent medicinal properties for ages. Journal of Functional Foods. Guarana is used for weight loss, to enhance athletic performance, as a stimulant, and to reduce mental and physical fatigue.It is a frequent addition to energy and weight loss products. Typically, guarana supplements are made by preparing an extract from the seeds or grinding the seeds into a powder. The effects of long-term administration of guarana on the cognition of normal, elderly volunteers. Traditionally, its roasted seeds and raw fruits were used to make beverages combining maté and other herbs. These products essentially negate any health benefits of guarana. When considering the use of herbal supplements, seek the advice of your doctor. If you choose to use guarana, use it as directed on the package or as directed by your doctor, pharmacist, or other healthcare provider. Do not take guarana without medical advice if you are using any of the following medications: stimulant drugs (amphetamines, ephedrine, nicotine, others); medications for depression or mental disorders; medications that slow blood-clotting: ardeparin (Normiflo), aspirin, clopidogrel (Plavix), diclofenac (Voltaren, Cataflam, others), dipyridamole (Persantine), ibuprofen (Advil, Motrin, others), naproxen (Anaprox, Naprosyn, others), dalteparin (Fragmin), enoxaparin (Lovenox), heparin, ticlopidine (Ticlid), warfarin (Coumadin), and others; any antibiotics or medication for fungal infections; This list is not complete. The effects of long-term administration of guarana on the cognition of normal, elderly volunteers. Consult with a licensed healthcare professional before using any herbal/health supplement. Guarana (Paullinia cupana) originated in the Amazon and was used by the Indians for its energising and appetite suppressant effects, as well as for treating diseases such as malaria and dysentry (this usage has since been forgotten, and was never proven). Int J Obes Relat Metab Disord. A seed paste, syrup, or extract is made from the guarana plant and then added to these drinks. There isn’t a clear dosage restriction on this substance, but most experts do not recommend consuming more than 800 mg per day. Over the eight weeks of treatment, this combination led to a significantly greater loss of weight and fat as well as larger reductions in hip circumference and serum triglyceride levels, as compared with placebo. These include guarana energy drinks or guarana alcohol products. Available for Android and iOS devices. Others suggest that it is just caffeine in guarana that has any effect. Traditionally, Amazonian tribes brewed the seeds of the guarana plant to make an energy drink, and for hundreds of years, Brazilians have used it as an invigorating tonic. Guarana (/ ɡ w ə ˈ r ɑː n ə / from the Portuguese guaraná [ɡwaɾɐˈna]), Paullinia cupana, syns. Amazonian tribes have embraced the use of guarana for centuries for its health benefits, among them its properties as an astringent and stimulant that help maintain your body’s proper nutritional levels during days of fasting. WebMD explains guarana's use as a weight loss supplement. Guarana is LIKELY SAFE. The Guarana extract Guaranine is the actual caffeine in the fruit. Sao Paulo Medical Journal. Members of this indigenous Amazon tribe were the first to prepare a drink with the seeds of guarana. Do not use excessive guarana if you are breast-feeding a baby. Avoid using stimulant drugs such as cocaine or amphetamines when using this product. There is also developing evidence that taking a specific combination product containing guarana, ephedra, and 17 other vitamins, minerals, and supplements helps reduce weight by approximately 2.7 kg over 8 weeks when used with a low-fat diet and exercise. Many people who consume beverages containing guarana are devotees, and they may not concern themselves with research that proves how the drinks make them feel. In fitness, guarana is used as a weight loss aid in weight loss products, supplements and oils. 2002. Guarana can give you young and glowing skin, shiny hair that is free of dandruff, and also cure most of the pathogenic infections on your skin and scalp. Galduroz JC and Carlini EA. Today, the Slow Food Foundation for Biodiversity recognizes the guarana plant as endangered and the industry as a threat to Mawé biocultural survival. This plant was introduced to western civilization in the 17th century following its discovery by Father Felip Betendorf (1). Subscribe to Drugs.com newsletters for the latest medication news, new drug approvals, alerts and updates. People often consume Guarana orally for the treatment of Obesity, boosting athletic performance, improving mental conditions, and is also used as an Aphrodisiac. Health and technological aspects of methylxanthines and polyphenols from guarana: A review. It is used as a stimulant and is used in sodas, tea, enrgy drinks and Brazilian cocoa. Each fruit contains about one seed, which contains approximately three times as much caffeine as coffee beans. Journal of Functional Foods 2018;47:457-468. doi:10.1016/j.jff.2018.05.048, Fukuda S. A potential biomarker for fatigue: Oxidative stress and anti-oxidative activity. 2016. Most often it is used by men to gain muscle mass and drying, but before you begin to take it, you need to consult with a specialist. This could go a long way toward promoting the adoption of more sustainable harvesting methods and protections for the Sateré-Mawé. Guarana is also sold in supplement form. It is used as a stimulant and is used in sodas, tea, enrgy drinks and Brazilian cocoa. Guarana, also called as Paullinia cupana, is a climbing Brazilian plant native to the Amazon basin.Different indigenous tribes in the dense forest of the Amazon used the fruit as a drink or ingredient in bread to benefit from its healing and energy boosting properties. may increase the presence of polycyclic aromatic hydrocarbons, Guarana (Paullinia cupana) improves fatigue in breast cancer patients undergoing systemic chemotherapy, Guarana (Paullinia cupana) presents a safe and effective anti-fatigue profile in patients with chronic kidney disease: A randomized, double-blind, three-arm, controlled clinical trial, Health and technological aspects of methylxanthines and polyphenols from guarana: A review, A potential biomarker for fatigue: Oxidative stress and anti-oxidative activity, Heart rate variability and cognitive function following a multi-vitamin and mineral supplementation with added guarana (Paullinia cupana), A double-blind, placebo-controlled, multi-dose evaluation of the acute behavioural effects of guaraná in humans, The effects of long-term administration of guarana on the cognition of normal, elderly volunteers, An herbal supplement containing Ma Huang-Guarana for weight loss: a randomized, double-blind trial, Lipid metabolism in trained rats: effect of guarana (Paullinia cupana Mart.) Therefore, it is used in many energy drinks and dietary supplements. Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances. Clinical Nutrition. Guarana, also known as Paullinia Cupana, is a seed that has more caffeine than coffee beans themselves. Caffeine is a stimulant and is most likely responsible for most of guarana's effects. The seeds are also rich in tannins and the stimulants theophylline and theobromine. Cathy Wong is a nutritionist and wellness expert. Guarana contains caffeine, a stimulant. “ One study indicated that guarana contains four times the amount of caffeine compared to coffee beans, so people may be highly sensitive to even a small amount of guarana,” says Kostro Miller. 2005. Guarana is often used as a weight loss aid. Guarana was widely used as an 'energy drink' by the Amazonian tribes during the hunting season due to the exuberance of caffeine, and the scant amount of theophylline and theobromine present in it. Therefore, it is used in many energy drinks and dietary supplements. It is thought to improve cognition, ease aching muscles, boost energy levels, and suppress the appetite. A double-blind, placebo-controlled, multi-dose evaluation of the acute behavioural effects of guarana in humans, Lipid metabolism in trained rats: effect of guarana (Mart.) Health Benefits of Cherry Juice for Arthritis and Gout. Are most guarana supplements sustainably harvested and fair trade? We comply with the HONcode standard for trustworthy health information -. Some studies suggest that the active ingredient of guarana was a chemical that was specific to the plant — guaranine. Guarana products differ in the amount of caffeine they contain. 11 Amazing Health Benefits of Guarana. doi:10.1038/sj.ijo.0801539, De Oliveira Campos, M. P., Riechelmann, R., Martins, L. C., Hassan, B. J., Casa, F. B. Whether you are treated by a medical doctor or a practitioner trained in the use of natural medicines/supplements, make sure all your healthcare providers know about all of your medical conditions and treatments. Guarana plant is named after the native Guarani Tribe of the Amazon Rainforests who used these seeds to brew a drink and even today Guarana finds its uses in multiple medicinal recipes. Guarana should also not be taken with alcohol or monoamine oxidase inhibitors (MAOIs), as combining these with caffeine may cause encephalopathy, neuromuscular irritability, hypotension, or sinus tachycardia, though this has not been well studied in patients taking guarana specifically. There is also developing evidence that taking a specific combination product containing guarana, ephedra, and 17 other vitamins, minerals, and supplements helps reduce weight by approximately 2.7 kg over 8 weeks when used with a low-fat diet and exercise. The stems, leaves, and roots of guarana are used as a fish-killing drug in Central and South America. It is thought to improve cognition, ease aching muscles, boost energy levels, and suppress the appetite. An herbal supplement containing Ma Huang-Guarana for weight loss: a randomized, double-blind trial. A dose of 70 mg guarana powder is on the lower end for available supplements, but is all you really need to get the benefits, which (for some uses) may actually lessen at higher doses. 118:88-93. doi:10.1016/j.biopsycho.2016.05.005. The effects of long-term administration of guarana on the cognition of normal, elderly volunteers. Tannins in guarana may aid in preventing loss of water during diarrhoea, preventing dehydration but only when taken at low doses. Guarana is a plant named for the Guarani tribe in the Amazon, who used the seeds to brew a drink. Note, however, that fewer than two tons of warana are put up for sale per year, and the Sateré-Mawé are not the source of most guarana supplements on the market. 114.1 1073-8. doi:10.1590/S1516-31801996000100003. In today’s growing market, guarana is more commonly located in flavorings, extracts, and syrups used in collaboration with the beverage industry. Nutrients. What is Guarana? … Haskell CF, Kennedy DO, Wesnes KA, Milne AL, Scholey AB. 1–7. Ask a doctor, pharmacist, or other healthcare provider if it is safe for you to use this product if you have: Guarana is considered possibly safe to use during pregnancy in small amounts. Research published in medical journal Appetite found that it helped prevent mental fatigue and improved cognitive performance. Biol Psychol. Guarana has been used by locals for centuries to improve digestive problems such as chronic diarrhea and constipation. Fukuda S, Nojima K, Motoki Y, Yamaguti K, Nakatomi Y, Okawa N, Fujiwara K, Watanabe Y, Kuratsune H. A potential biomarker for fatigue: oxidative stress and anti-oxidative activity. Why is it good for your skin? Guarana is often used as an energy booster, a dietary supplement, and a flavoring agent. Guarana is often sold as an herbal supplement. Guarana should not be used in place of medication prescribed for you by your doctor. Using different formulations together increases the risk of an overdose. [ 4] Do not use excessive guarana if you are breast-feeding a baby. There is no scientific evidence that guarana extracts or berries contain any other therapeutical use. Guarana has one of … supplementation. Some energy drinks contain guarana seed extract. Seek emergency medical attention or call the Poison Help line at 1-800-222-1222. Nevertheless, it's worth digging into what is proven (and not). Guarana has played an important role in the Amazonian Indians' society. It sometimes is mixed with alcohol to prepare a more intoxicating beverage. Other drugs may interact with guarana, including prescription and over-the-counter medicines, vitamins, and herbal products. diabetes; high blood pressure; glaucoma; irritable bowel syndrome; osteoporosis; or. Guarana is a tiny berry packed with the potent power needed to provide a variety of health benefits – yet one more example of how big things can come in small packages. Combining guarana with other stimulants like yerba mate, diet aids, or performance-enhancing supplements may lead to palpitations, arrhythmias, high blood pressure, seizures, and other adverse effects. The fact that it is rich in antioxidants, specifically tannins is what helps it to treat and relieve chronic diarrhea. Doses greater than 250-300 mg daily have been linked to side effects. Taking guarana along with mate and damiana seems to increase weight loss. The fact that it is rich in antioxidants, specifically tannins is what helps it to treat and relieve chronic diarrhea. It is a frequent addition to energy and weight loss products. Guarana is often sold as an herbal supplement. Guarana contains a large amount of caffeine, and the precise amount may not be properly documented on the label. There are no regulated manufacturing standards in place for many herbal compounds and some marketed supplements have been found to be contaminated with toxic metals or … Guarana is possibly safe in children in low amounts (caffeine levels found in foods). Lipid metabolism in trained rats: effect of guarana (Paullinia cupana Mart.) Another double-blind, placebo-controlled study of guarana use throughout the day found that guarana improved secondary memory performance, mood, and alertness at low (37.5 mg, 75 mg) and higher (150 mg, 300 mg) doses, with the lower doses being more effective., While this data is promising for acute uses, a study examining the use of guarana, caffeine, and placebo on the cognition of 45 older individuals found no significant lasting effects of guarana on cognition long-term.. Get emergency medical help if you have signs of an allergic reaction: hives; difficulty breathing; swelling of your face, lips, tongue, or throat. 2001;25(3):316-324. doi:10.1038/sj.ijo.0801539, Lima WP, Carnevali LC Jr, Eder R, Costa Rosa LF, Bacchi EM, Seelaender MC. There are no regulated manufacturing standards in place for many herbal compounds and some marketed supplements have been found to be contaminated with toxic metals or other drugs. 1. Guarana is an Amazonian fruit-bearing plant that has been used traditionally by natives of the Amazons and Brazil. You can find Guarana in many soft drinks and energy drinks because of its energy-boosting properties. The guarana plant is traditionally used to help prevent and treat malaria. Guarana has been used for centuries as a natural stomach tonic to treat digestive problems like chronic diarrhea and constipation . Do not use different formulations of guarana (such as tablets, extracts, and others) at the same time, unless specifically directed to do so by a health care professional. Medicinal use of this product has not been approved by the FDA. The highest degree of quality control for guarana supplements can be found in those made by the Sateré-Mawé people, who continue to harvest the plant through traditional methods. Guarana is often used in products for cellulitis, based on its high content of caffeine and alkaloids. Nutrients. Guaraná has been used in body care products for its tonifying and astringent properties, and to reduce cellulite. Drinks that this are often pumped full of unhealthy added sugar and extra ingredients. International Journal of Obesity. Guarana has been found to decrease platelet aggregation and thromboxane synthesis, so it may increase the risk of bleeding when taken with aspirin, anticoagulants such as Coumadin (warfarin), and platelet inhibitors such as Ticlid (ticlopidine) and Plavix (clopidogrel). For the indigenous of south America, Guarana used to be as highly valued as Gold was by the Europeans. Thank you, {{form.email}}, for signing up. The caffeine in guarana might block the affects of adenosine (Adenocard). However, since this time the myths and legends regarding it’s health properties have grown exponentially. Products containing guarana are possibly safe when taken by mouth and for a short period of time. You may report side effects to FDA at 1-800-FDA-1088. Guarana extracts are used as a key ingredient in energy drinks due to the high caffeine levels. The plant was also used for its astringent properties. 3. You may not be able to use guarana if you have certain medical conditions. Guarana is a plant and it is also known as Brazilian Cocoa, Cacao Brésilien, Guarana Seed Extract, Guaranine, Paullinia cupana, Paullinia sorbilis, Zoom. Some uses not proven with research have included treatment of anxiety, improvement of mental performance, weight loss, malaria, diarrhea, fever, headaches, heart problems, enhancement of athletic performance, chronic fatigue syndrome, joint pain, fluid retention and others. P. crysan, P. sorbilis) is a climbing plant in the family Sapindaceae, native to the Amazon basin and especially common in Brazil. Select one or more newsletters to continue. Guarana contains more than 2.5% to 5% caffeine by weight. Guarana (Paullinia cupana) presents a safe and effective anti-fatigue profile in patients with chronic kidney disease: A randomized, double-blind, three-arm, controlled clinical trial. This includes angelica (dong quai), capsicum, clove, danshen, garlic, ginger, ginkgo, green tea, horse chestnut, panax ginseng, poplar, red clover, saw palmetto, turmeric, and willow. The seeds of the guarana fruit are about the size of coffee beans, but they contain more than twice as much caffeine, along with other compounds. J Psychopharmacol. 47:457-468. doi:10.1016/j.jff.2018.05.048, Ⓒ 2021 About, Inc. (Dotdash) — All rights reserved, Verywell Health uses only high-quality sources, including peer-reviewed studies, to support the facts within our articles. If you need a cardiac stress test you should stop taking guarana at least 24 hours before your test. 2018. Guarana can be crushed to make primal fruit pulp. Manages Anxiety And Neurodegenerative Disorders. 21(1):65-70. doi:10.1177/0269881106063815. The study of breast cancer patients used a 50 milligram (mg) dose twice daily, and the study in patients with chronic kidney disease examined the effects of doses as high as 200 mg and 400 mg, indicating anti-fatigue effects at low and high doses. De Oliveira Campos MP, Riechelmann R, Martins LC, Hassan BJ, Casa FB, Del Giglio A. Guarana (Paullinia cupana) improves fatigue in breast cancer patients undergoing systemic chemotherapy. Guarana powder can have protective effects on your brain and nervous system. It often is Ask them about their harvesting methods and what they are doing to protect and support the originators of this ecological knowledge. diarrhea. Guarana is considered possibly safe to use during pregnancy in small amounts. Guarana is a natural herbal supplement. species of climbing plant native to the Amazon regions known for its stimulant and medicinal properties 2007;21(1):65-70. doi:10.1177/0269881106063815, Galduróz JC, Carlini EA. supplementation. Data sources include IBM Watson Micromedex (updated 7 Dec 2020), Cerner Multum™ (updated 4 Jan 2021), ASHP (updated 3 Dec 2020) and others. : Oxidative stress and anti-oxidative activity reactions associated with guarana does not improve, more! Weight loss in Central and South America sign up for our health Tip of Amazon. On your brain and nervous system seeds into a powder, as a,... Studies suggest that it is most likely responsible for most of guarana 's use as a weight loss Hays A.... That it is thought to improve digestive problems like chronic diarrhea and constipation milk and can affect a nursing.... ; high blood pressure ; glaucoma ; irritable bowel syndrome ; osteoporosis ; or,,! 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World due to its high content of caffeine among plants, and to ease symptoms of diarrhoea, depending how... Licensed naturopathic doctor with a licensed healthcare professional before using any herbal/health supplement herbal teas and dietary supplement.! Of Functional foods 2018 ; 47:457-468. doi:10.1016/j.jff.2018.05.048, Fukuda S. a potential biomarker for:! New drug approvals, alerts and updates food foundation for Biodiversity recognizes the guarana plant a! Keep you alert for longer and updates only when taken at low doses when taken mouth... Which is what is guarana used for to a planned activity in order to receive maximum benefits focus. And over-the-counter medicines and natural health L., Macedo, G. a as tablets best. Beverage used like tea or coffee guarana can also be used in sodas, tea enrgy... Allow you to focus high content of caffeine as coffee beans you should not mistake guarana... 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